An overview on ethical considerations in stem cell research in Iran and ethical recommendations:a review

An overview on ethical considerations in stem cell research in Iran and ethical recommendations:a review

Farajkhoda, Tahmineh

2017/02/00

English

20170200

Conducting research on the stem cell lines might bring some worthy good to public. Human Stem Cells (hSCs) research has provided opportunities for scientific progresses and new therapies, but some complex ethical matters should be noticed to ensure that stem cell research is carried out in an ethically appropriate manner. The aim of this review article is to discuss the importance of stem cell research, code of ethics for stem cell research in Iran and ethical recommendation. Generation of stem cells for research from human embryo or adult stem cells, saving, maintenance and using of them are the main ethical, legal and jurisprudence concerns in Iran. Concerns regarding human reproduction or human cloning, breach of human dignity, genetic manipulation and probability of tumorogenisity are observed in adult/somatic stem cells. Destruction of embryo to generate stem cell is an important matter in Iran. In this regards, obtaining stem cell from donated frozen embryos through infertility treatment that would be discarded is an acceptable solution in Iran for generation of embryo for research. Ethical, legal, and jurisprudence strategies for using adult/somatic stem cells are determination of ownership of stem cells, trade prohibition of human body, supervision on bio banks and information of Oversight Committee on Stem Cell Research. Recommendations to handle ethical issues for conducting stem cell research are well-designed studies, compliance codes of ethics in biomedical research (specifically codes of ethics on stem cell research, codes of ethics on clinical trials studies and codes of ethics on animals studies), appropriate collaboration with ethics committees and respecting of rights of participants (including both of human and animal rights) in research. In addition, there is a necessity for extending global networks of bioethics for strengthening communications within organizations at both the regional and international level, strengthening legislation systems, designing and establishing convenient collaborative educational courses at different levels.

18.7

18.7;15.1;1.2

research ethics--[pri];stem cells--pri]

adult stem cells;bioethics;cell lines;codes of ethics;common good;embryonic stem cells;induced pluripotent stem cells;Islamic ethics;risks and benefits;sharia;transplantation;la darar wa la dirar

Iran--[pri]

dharurah;maslaha

International Journal of Reproductive Biomedicine (Yazd)2017 February; 15(2):67-74

Creative Commons Attribution License 3.0

citation

e

67 refs

24764108 (print);24763772 (online)